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ea0029p1378 | Pituitary Clinical | ICEECE2012

Low IGF1 levels are associated with a lower prevalence and incidence of anxiety disorders in primary care patients (DETECT cohort) and the general population (SHIP cohort)

Sievers C. , Auer M. , Klotsche J. , Pieper L. , Athanasoulia A. , Schneider H. , Marz W. , Nauck M. , Volzke H. , John U. , Freyberger H. , Friedrich N. , Biffar R. , Wittchen H. , Stalla G. , Wallaschofski H. , Grabe H.

Objective: In vitro and in vivo models revealed that the somatotropic system exerts central effects on the central nervous system. The objective of this study was to investigate for the first time whether varying endogenous IGF1 levels are associated with mental health outcomes, namely affective disorders, in humans.Design and methods: We included 6773 subjects from the DETECT study, a representative study on primary care patients in German...

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Low IGF1 levels are associated with a lower prevalence and incidence of anxiety disorders in primary care patients (DETECT cohort) and the general population (SHIP cohort)

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